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Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis

Microgliosis is a major hallmark of Alzheimer’s disease (AD) brain pathology. Aβ peptide is hypothesized to act as a stimulus for microglia leading to activation of non-receptor tyrosine kinases and subsequent secretion of pro-inflammatory cytokines. Therefore, the signaling pathways mediating micro...

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Detalles Bibliográficos
Autores principales:	Manocha, Gunjan D., Puig, Kendra L., Austin, Susan A., Seyb, Kathleen, Glicksman, Marcie A., Combs, Colin K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498792/ https://www.ncbi.nlm.nih.gov/pubmed/26161952 http://dx.doi.org/10.1371/journal.pone.0132604

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