HIV drug resistance mutations following poor adherence in HIV-infected patient: a case report

Acquired HIV drug resistance following poor adherence is common. We report a case of HIV-infected patient with poor CD4 gain and self reported poor adherence. Investigations revealed high viral load and resistance to NRTIs and NNRTIs with sensitivity to boosted PIs. HIVDR mutations create treatment...

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Detalles Bibliográficos
Autores principales: Masikini, Peter, Mpondo, Bonaventura C T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498841/
https://www.ncbi.nlm.nih.gov/pubmed/26185627
http://dx.doi.org/10.1002/ccr3.254
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author Masikini, Peter
Mpondo, Bonaventura C T
author_facet Masikini, Peter
Mpondo, Bonaventura C T
author_sort Masikini, Peter
collection PubMed
description Acquired HIV drug resistance following poor adherence is common. We report a case of HIV-infected patient with poor CD4 gain and self reported poor adherence. Investigations revealed high viral load and resistance to NRTIs and NNRTIs with sensitivity to boosted PIs. HIVDR mutations create treatment challenges in resource limited settings.
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spelling pubmed-44988412015-07-16 HIV drug resistance mutations following poor adherence in HIV-infected patient: a case report Masikini, Peter Mpondo, Bonaventura C T Clin Case Rep Case Reports Acquired HIV drug resistance following poor adherence is common. We report a case of HIV-infected patient with poor CD4 gain and self reported poor adherence. Investigations revealed high viral load and resistance to NRTIs and NNRTIs with sensitivity to boosted PIs. HIVDR mutations create treatment challenges in resource limited settings. John Wiley & Sons, Ltd 2015-06 2015-03-29 /pmc/articles/PMC4498841/ /pubmed/26185627 http://dx.doi.org/10.1002/ccr3.254 Text en © 2015 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Masikini, Peter
Mpondo, Bonaventura C T
HIV drug resistance mutations following poor adherence in HIV-infected patient: a case report
title HIV drug resistance mutations following poor adherence in HIV-infected patient: a case report
title_full HIV drug resistance mutations following poor adherence in HIV-infected patient: a case report
title_fullStr HIV drug resistance mutations following poor adherence in HIV-infected patient: a case report
title_full_unstemmed HIV drug resistance mutations following poor adherence in HIV-infected patient: a case report
title_short HIV drug resistance mutations following poor adherence in HIV-infected patient: a case report
title_sort hiv drug resistance mutations following poor adherence in hiv-infected patient: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498841/
https://www.ncbi.nlm.nih.gov/pubmed/26185627
http://dx.doi.org/10.1002/ccr3.254
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