Digynic triploidy: utility and challenges of noninvasive prenatal testing

Low fraction fetal DNA in noninvasive prenatal testing in the context of fetal growth restriction and multiple congenital anomalies should alert medical professionals to the possibility of digynic triploidy. Single-nucleotide polymorphism microarray can detect the parental origin of triploidy and ex...

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Detalles Bibliográficos
Autores principales: Fleischer, Julie, Shenoy, Archana, Goetzinger, Katherine, Cottrell, Catherine E, Baldridge, Dustin, White, Frances V, Shinawi, Marwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498852/
https://www.ncbi.nlm.nih.gov/pubmed/26185638
http://dx.doi.org/10.1002/ccr3.247
Descripción
Sumario:Low fraction fetal DNA in noninvasive prenatal testing in the context of fetal growth restriction and multiple congenital anomalies should alert medical professionals to the possibility of digynic triploidy. Single-nucleotide polymorphism microarray can detect the parental origin of triploidy and explain its mechanism.

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