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Potentially lethal ACE-inhibitor-induced angioedema in a child

We report a case of a 9-year-old female with known end-stage kidney disease who presented with sudden onset tongue swelling. A diagnosis of angiotensin-converting enzyme inhibitor-induced angioedema related to bradykinin accumulation was made. Her symptoms resolved shortly after discontinuation of c...

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Detalles Bibliográficos
Autores principales: Bukhari, Esraa, Safdar, Osama Y, Shalaby, Mohammed, AlSharif, Shafiqa MJ, Alsufiany, Khoulod, Kari, Jameela A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498856/
https://www.ncbi.nlm.nih.gov/pubmed/26185642
http://dx.doi.org/10.1002/ccr3.265
Descripción
Sumario:We report a case of a 9-year-old female with known end-stage kidney disease who presented with sudden onset tongue swelling. A diagnosis of angiotensin-converting enzyme inhibitor-induced angioedema related to bradykinin accumulation was made. Her symptoms resolved shortly after discontinuation of captopril. Early diagnosis can save patients from severe upper airway obstruction.