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Neutralizing Anti-IL20 Antibody Treatment Significantly Modulates Low Grade Inflammation without Affecting HbA1c in Type 2 Diabetic db/db Mice

Low grade inflammation is present in pre-clinical and human type 2 diabetes. In this process, several cytokines like IL-1β and inflammatory cells like macrophages are activated and demonstrated to participate to the disease initiation and progression. IL-20 is a cytokine known to play non-redundant...

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Detalles Bibliográficos
Autores principales: Mayer, Christopher, Bergholdt, Regine, Cucak, Helena, Rolin, Bidda Charlotte, Sams, Anette, Rosendahl, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498892/
https://www.ncbi.nlm.nih.gov/pubmed/26162095
http://dx.doi.org/10.1371/journal.pone.0131306