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Central chondrosarcoma progression is associated with pRb pathway alterations: CDK4 down-regulation and p16 overexpression inhibit cell growth in vitro

Chondrosarcomas are highly resistant to conventional radiation and chemotherapy, and surgical removal is the only option for curative treatment. Consequently, there is nothing to offer patients with inoperable tumours and metastatic disease. The aim of this study is to investigate genes involved in...

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Detalles Bibliográficos
Autores principales:	Schrage, Yvonne M, Lam, Suzanne, Jochemsen, Aart G, Cleton-Jansen, Anne-Marie, Taminiau, Antonie HM, Hogendoorn, Pancras CW, Bovée, Judith VMG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Ltd 2009
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498940/ https://www.ncbi.nlm.nih.gov/pubmed/18624751 http://dx.doi.org/10.1111/j.1582-4934.2008.00406.x

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