Cargando…
Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits
Protein phosphatase-1 (PP1) is a key regulator of transcription and is targeted to promoter regions via associated proteins. However, the chromatin binding sites of PP1 have never been studied in a systematic and genome-wide manner. Methylation-based DamID profiling in HeLa cells has enabled us to m...
Autores principales: | Verheyen, Toon, Görnemann, Janina, Verbinnen, Iris, Boens, Shannah, Beullens, Monique, Van Eynde, Aleyde, Bollen, Mathieu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499128/ https://www.ncbi.nlm.nih.gov/pubmed/25990731 http://dx.doi.org/10.1093/nar/gkv500 |
Ejemplares similares
-
The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets
por: Van Dessel, Nele, et al.
Publicado: (2010) -
NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes
por: Minnebo, Nikki, et al.
Publicado: (2013) -
The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis
por: Ferreira, Mónica, et al.
Publicado: (2017) -
Enhanced DNA-repair capacity and resistance to chemically induced carcinogenesis upon deletion of the phosphatase regulator NIPP1
por: Verbinnen, Iris, et al.
Publicado: (2020) -
Functions and therapeutic potential of protein phosphatase 1: Insights from mouse genetics()
por: Ferreira, Mónica, et al.
Publicado: (2019)