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DNA(3′)pp(5′)G de-capping activity of aprataxin: effect of cap nucleoside analogs and structural basis for guanosine recognition
DNA(3′)pp(5′)G caps synthesized by the 3′-PO(4)/5′-OH ligase RtcB have a strong impact on enzymatic reactions at DNA 3′-OH ends. Aprataxin, an enzyme that repairs A(5′)pp(5′)DNA ends formed during abortive ligation by classic 3′-OH/5′-PO(4) ligases, is also a DNA 3′ de-capping enzyme, converting DNA...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499129/ https://www.ncbi.nlm.nih.gov/pubmed/26007660 http://dx.doi.org/10.1093/nar/gkv501 |