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ATP-dependent G-quadruplex unfolding by Bloom helicase exhibits low processivity

Various helicases and single stranded DNA (ssDNA) binding proteins unfold G-quadruplex (GQ) structures. However, the underlying mechanisms of this activity have only recently come to focus. We report kinetic studies on Bloom (BLM) helicase and human telomeric GQ interactions using single-molecule Fö...

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Detalles Bibliográficos
Autores principales:	Budhathoki, Jagat B., Stafford, Edward J., Yodh, Jaya G., Balci, Hamza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499149/ https://www.ncbi.nlm.nih.gov/pubmed/25990739 http://dx.doi.org/10.1093/nar/gkv531

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