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Structure-guided sequence specificity engineering of the modification-dependent restriction endonuclease LpnPI

The eukaryotic Set and Ring Associated (SRA) domains and structurally similar DNA recognition domains of prokaryotic cytosine modification-dependent restriction endonucleases recognize methylated, hydroxymethylated or glucosylated cytosine in various sequence contexts. Here, we report the apo-struct...

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Detalles Bibliográficos
Autores principales:	Sasnauskas, Giedrius, Zagorskaitė, Evelina, Kauneckaitė, Kotryna, Tamulaitiene, Giedre, Siksnys, Virginijus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499157/ https://www.ncbi.nlm.nih.gov/pubmed/26001968 http://dx.doi.org/10.1093/nar/gkv548

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