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Outwitting EF-Tu and the ribosome: translation with d-amino acids

Key components of the translational apparatus, i.e. ribosomes, elongation factor EF-Tu and most aminoacyl-tRNA synthetases, are stereoselective and prevent incorporation of d-amino acids (d-aa) into polypeptides. The rare appearance of d-aa in natural polypeptides arises from post-translational modi...

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Detalles Bibliográficos
Autores principales:	Achenbach, John, Jahnz, Michael, Bethge, Lucas, Paal, Krisztina, Jung, Maria, Schuster, Maja, Albrecht, Renate, Jarosch, Florian, Nierhaus, Knud H., Klussmann, Sven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499158/ https://www.ncbi.nlm.nih.gov/pubmed/26026160 http://dx.doi.org/10.1093/nar/gkv566

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