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Saturated and mono-unsaturated lysophosphatidylcholine metabolism in tumour cells: a potential therapeutic target for preventing metastases
BACKGROUND: Metastasis is the leading cause of mortality in malignant diseases. Patients with metastasis often show reduced Lysophosphatidylcholine (LysoPC) plasma levels and treatment of metastatic tumour cells with saturated LysoPC species reduced their metastatic potential in vivo in mouse experi...
Autores principales: | Raynor, Anna, Jantscheff, Peter, Ross, Thomas, Schlesinger, Martin, Wilde, Maurice, Haasis, Sina, Dreckmann, Tim, Bendas, Gerd, Massing, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499168/ https://www.ncbi.nlm.nih.gov/pubmed/26162894 http://dx.doi.org/10.1186/s12944-015-0070-x |
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