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Hyperoxia-induced methylation decreases RUNX3 in a newborn rat model of bronchopulmonary dysplasia

BACKGROUND: Bronchopulmonary dysplasia (BPD) in premature infants is a predominantly secondary occurrence to intrauterine inflammation/infection and postpartum mechanical ventilation; in recent years, an association with epigenetics has also been found. DNA methylation, catalyzed by DNA methyl trans...

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Detalles Bibliográficos
Autores principales: Zhu, Yuting, Fu, Jianhua, Yang, Haiping, Pan, Yuqing, Yao, Li, Xue, Xindong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499173/
https://www.ncbi.nlm.nih.gov/pubmed/26104385
http://dx.doi.org/10.1186/s12931-015-0239-x

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