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The production of alpha/beta and gamma/delta double negative (DN) T-cells and their role in the maintenance of pregnancy
The ability of the thymus gland to convert bone marrow-derived progenitor cells into single positive (SP) T-cells is well known. In this review we present evidence that the thymus, in addition to producing SP T-cells, also has a pathway for the production of double negative (DN) T-cells. The existen...
Autores principales: | Chapman, John C., Chapman, Fae M., Michael, Sandra D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499209/ https://www.ncbi.nlm.nih.gov/pubmed/26164866 http://dx.doi.org/10.1186/s12958-015-0073-5 |
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