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Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients

Introduction. The anatomic position of the sentinel lymph node is variable. The purpose of the following study was to assess the dose distribution delivered to the surgically marked sentinel lymph node site by 3D conformal radio therapy technique. Material and Method. We retrospectively analysed 70...

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Autores principales: Witucki, Gerlo, Degregorio, Nikolaus, Rempen, Andreas, Schwentner, Lukas, Bottke, Dirk, Janni, Wolfgang, Ebner, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499384/
https://www.ncbi.nlm.nih.gov/pubmed/26221542
http://dx.doi.org/10.1155/2015/539842
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author Witucki, Gerlo
Degregorio, Nikolaus
Rempen, Andreas
Schwentner, Lukas
Bottke, Dirk
Janni, Wolfgang
Ebner, Florian
author_facet Witucki, Gerlo
Degregorio, Nikolaus
Rempen, Andreas
Schwentner, Lukas
Bottke, Dirk
Janni, Wolfgang
Ebner, Florian
author_sort Witucki, Gerlo
collection PubMed
description Introduction. The anatomic position of the sentinel lymph node is variable. The purpose of the following study was to assess the dose distribution delivered to the surgically marked sentinel lymph node site by 3D conformal radio therapy technique. Material and Method. We retrospectively analysed 70 radiotherapy (RT) treatment plans of consecutive primary breast cancer patients with a successful, disease-free, sentinel lymph node resection. Results. In our case series the SN clip volume received a mean dose of 40.7 Gy (min 28.8 Gy/max 47.6 Gy). Conclusion. By using surgical clip markers in combination with 3D CT images our data supports the pathway of tumouricidal doses in the SN bed. The target volume should be defined by surgical clip markers and 3D CT images to give accurate dose estimations.
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spelling pubmed-44993842015-07-28 Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients Witucki, Gerlo Degregorio, Nikolaus Rempen, Andreas Schwentner, Lukas Bottke, Dirk Janni, Wolfgang Ebner, Florian Int J Breast Cancer Research Article Introduction. The anatomic position of the sentinel lymph node is variable. The purpose of the following study was to assess the dose distribution delivered to the surgically marked sentinel lymph node site by 3D conformal radio therapy technique. Material and Method. We retrospectively analysed 70 radiotherapy (RT) treatment plans of consecutive primary breast cancer patients with a successful, disease-free, sentinel lymph node resection. Results. In our case series the SN clip volume received a mean dose of 40.7 Gy (min 28.8 Gy/max 47.6 Gy). Conclusion. By using surgical clip markers in combination with 3D CT images our data supports the pathway of tumouricidal doses in the SN bed. The target volume should be defined by surgical clip markers and 3D CT images to give accurate dose estimations. Hindawi Publishing Corporation 2015 2015-06-28 /pmc/articles/PMC4499384/ /pubmed/26221542 http://dx.doi.org/10.1155/2015/539842 Text en Copyright © 2015 Gerlo Witucki et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Witucki, Gerlo
Degregorio, Nikolaus
Rempen, Andreas
Schwentner, Lukas
Bottke, Dirk
Janni, Wolfgang
Ebner, Florian
Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_full Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_fullStr Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_full_unstemmed Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_short Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_sort evaluation of sentinel lymph node dose distribution in 3d conformal radiotherapy techniques in 67 pn0 breast cancer patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499384/
https://www.ncbi.nlm.nih.gov/pubmed/26221542
http://dx.doi.org/10.1155/2015/539842
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