Cargando…

Trimethyltin-Induced Microglial Activation via NADPH Oxidase and MAPKs Pathway in BV-2 Microglial Cells

Trimethyltin (TMT) is known as a potent neurotoxicant that causes neuronal cell death and neuroinflammation, particularly in the hippocampus. Microglial activation is one of the prominent pathological features of TMT neurotoxicity. Nevertheless, it remains unclear how microglial activation occurs in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Da Jung, Kim, Yong Sik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499416/ https://www.ncbi.nlm.nih.gov/pubmed/26221064 http://dx.doi.org/10.1155/2015/729509

Ejemplares similares

NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration
por: Qin, Liya, et al.
Publicado: (2012)

The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease
por: Wilkinson, Brandy L, et al.
Publicado: (2006)

Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase
por: Jiang, Lulu, et al.
Publicado: (2016)

Salidroside Reduces Cell Mobility via NF-κB and MAPK Signaling in LPS-Induced BV2 Microglial Cells
por: Hu, Haixia, et al.
Publicado: (2014)

Hispidin inhibits LPS-induced nitric oxide production in BV-2 microglial cells via ROS-dependent MAPK signaling
por: Jin, Mei-Hua, et al.
Publicado: (2021)

Microglial Cells Are Involved in the Susceptibility of NADPH Oxidase Knockout Mice to 6-Hydroxy-Dopamine-Induced Neurodegeneration
por: Hernandes, Marina S., et al.
Publicado: (2013)

PACAP and VIP Modulate LPS-Induced Microglial Activation and Trigger Distinct Phenotypic Changes in Murine BV2 Microglial Cells
por: Karunia, Jocelyn, et al.
Publicado: (2021)

Anthocyanins Downregulate Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglial Cells by Suppressing the NF-κB and Akt/MAPKs Signaling Pathways
por: Jeong, Jin-Woo, et al.
Publicado: (2013)

Lipoxin A4 Regulates Lipopolysaccharide-Induced BV2 Microglial Activation and Differentiation via the Notch Signaling Pathway
por: Wu, Jun, et al.
Publicado: (2019)

Involvement of NFƙB and MAPK signaling pathways in the preventive effects of Ganoderma lucidum on the inflammation of BV-2 microglial cells induced by LPS
por: Hilliard, Aaron, et al.
Publicado: (2020)

Quercus acuta Thunb. Suppresses LPS-Induced Neuroinflammation in BV2 Microglial Cells via Regulating MAPK/NF-κB and Nrf2/HO-1 Pathway
por: Kim, Jae Kwang, et al.
Publicado: (2022)

LPS-Induced proNGF Synthesis and Release in the N9 and BV2 Microglial Cells: A New Pathway Underling Microglial Toxicity in Neuroinflammation
por: Duan, Li, et al.
Publicado: (2013)

Anti-Inflammatory and Anti-Migratory Activities of Isoquinoline-1-Carboxamide Derivatives in LPS-Treated BV2 Microglial Cells via Inhibition of MAPKs/NF-κB Pathway
por: Do, Ha Thi Thu, et al.
Publicado: (2020)

Effects of ginsenoside Re on LPS-induced inflammatory mediators in BV2 microglial cells
por: Lee, Kang-Woo, et al.
Publicado: (2012)

Microglial- and Astrocyte-Specific Expression of Purinergic Signaling Components and Inflammatory Mediators in the Rat Hippocampus During Trimethyltin-Induced Neurodegeneration
por: Dragić, Milorad, et al.
Publicado: (2021)

trans-Cinnamaldehyde Inhibits Microglial Activation and Improves Neuronal Survival against Neuroinflammation in BV2 Microglial Cells with Lipopolysaccharide Stimulation
por: Fu, Yan, et al.
Publicado: (2017)

Steppogenin Isolated from Cudrania tricuspidata Shows Antineuroinflammatory Effects via NF-κB and MAPK Pathways in LPS-Stimulated BV2 and Primary Rat Microglial Cells
por: Kim, Dong-Cheol, et al.
Publicado: (2017)

PACAP and VIP Mitigate Rotenone-Induced Inflammation in BV-2 Microglial Cells
por: Broome, Sarah Thomas, et al.
Publicado: (2022)

Prenylated Flavonoids from Cudrania tricuspidata Suppress Lipopolysaccharide-Induced Neuroinflammatory Activities in BV2 Microglial Cells
por: Kim, Dong-Cheol, et al.
Publicado: (2016)

Monascin ameliorate inflammation in the lipopolysaccharide-induced BV-2 microglial cells via suppressing the NF-κB/p65 pathway
por: Shi, Yong-Xiang, et al.
Publicado: (2020)

Quercetin Attenuates Inflammatory Responses in BV-2 Microglial Cells: Role of MAPKs on the Nrf2 Pathway and Induction of Heme Oxygenase-1
por: Sun, Grace Y., et al.
Publicado: (2015)

Aluminum-Induced Alterations in Purinergic System Parameters of BV-2 Brain Microglial Cells
por: Assmann, Charles Elias, et al.
Publicado: (2021)

Anti-Inflammatory Effect of Wasp Venom in BV-2 Microglial Cells in Comparison with Bee Venom
por: Yun, Hyun Seok, et al.
Publicado: (2021)

Anti-Inflammatory Effect of Ginsenoside Rg5 in Lipopolysaccharide-Stimulated BV2 Microglial Cells
por: Lee, Yu Young, et al.
Publicado: (2013)

Sinomenine, a natural dextrorotatory morphinan analog, is anti-inflammatory and neuroprotective through inhibition of microglial NADPH oxidase
por: Qian, Li, et al.
Publicado: (2007)

Antineuroinflammatory Effect of Amburana cearensis and Its Molecules Coumarin and Amburoside A by Inhibiting the MAPK Signaling Pathway in LPS-Activated BV-2 Microglial Cells
por: de Araújo, Ana Bruna, et al.
Publicado: (2022)

2-cyclohexylamino-5,8-dimethoxy-1,4-naphthoquinone inhibits LPS-induced BV2 microglial activation through MAPK/NF-kB signaling pathways
por: Sun, Hu-Nan, et al.
Publicado: (2016)

Antineuroinflammatory Effects of 7,3’,4’-Trihydroxyisoflavone in Lipopolysaccharide-Stimulated BV2 Microglial Cells through MAPK and NF-κB Signaling Suppression
por: Kim, Seon-Kyung, et al.
Publicado: (2021)

Naegleria fowleri Extracellular Vesicles Induce Proinflammatory Immune Responses in BV-2 Microglial Cells
por: Lê, Hương Giang, et al.
Publicado: (2023)

Investigations into the Role of Metabolism in the Inflammatory Response of BV2 Microglial Cells
por: Maher, Pamela
Publicado: (2021)

Naegleria fowleri Cathepsin B Induces a Pro-Inflammatory Immune Response in BV-2 Microglial Cells via NF-κB and AP-1 Dependent-MAPK Signaling Pathway
por: Lê, Hương Giang, et al.
Publicado: (2022)

Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration
por: Mander, Palwinder, et al.
Publicado: (2005)

2,5-Hexanedione induces dopaminergic neurodegeneration through integrin α(M)β2/NADPH oxidase axis-mediated microglial activation
por: Zhang, Cong, et al.
Publicado: (2018)

Determining the role of IL-4 induced neuroinflammation in microglial activity and amyloid-β using BV2 microglial cells and APP/PS1 transgenic mice
por: Latta, Clare H, et al.
Publicado: (2015)

The inhibitory effects of Orengedokuto on inducible PGE2 production in BV-2 microglial cells
por: Iwata, Yoshika, et al.
Publicado: (2021)

PapRIV, a BV-2 microglial cell activating quorum sensing peptide
por: Janssens, Yorick, et al.
Publicado: (2021)

3,4,5-Trihydroxycinnamic Acid Inhibits Lipopolysaccharide-Induced Inflammatory Response through the Activation of Nrf2 Pathway in BV2 Microglial Cells
por: Lee, Jae-Won, et al.
Publicado: (2013)

Dual RNA Sequencing Reveals the Expression of Unique Transcriptomic Signatures in Lipopolysaccharide-Induced BV-2 Microglial Cells
por: Das, Amitabh, et al.
Publicado: (2015)

Resolvin D1 promotes the interleukin-4-induced alternative activation in BV-2 microglial cells
por: Li, Longyan, et al.
Publicado: (2014)

Qingkailing Suppresses the Activation of BV2 Microglial Cells by Inhibiting Hypoxia/Reoxygenation-Induced Inflammatory Responses
por: Mana, Lulu, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lg0iduss8td6lbq7dfb04eskdu