Cargando…

p38 MAPK and PI3K/AKT Signalling Cascades inParkinson’s Disease

Parkinson's disease (PD) is a chronic neurodegenerative condition which has the second largest incidence rate among all other neurodegenerative disorders barring Alzheimer's disease (AD). Currently there is no cure and researchers continue to probe the therapeutic prospect in cell cultures...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jha, Saurabh Kumar, Jha, Niraj Kumar, Kar, Rohan, Ambasta, Rashmi K, Kumar, Pravir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Babol University of Medical Sciences 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499569/ https://www.ncbi.nlm.nih.gov/pubmed/26261796

Ejemplares similares

Comparative study of anti-angiogenic activities of luteolin, lectin and lupeol biomolecules
por: Ambasta, Rashmi K., et al.
Publicado: (2015)

CREB1(K292) and HINFP(K330) as Putative Common Therapeutic Targets in Alzheimer’s and Parkinson’s Disease
por: Gupta, Rohan, et al.
Publicado: (2021)

Nanoparticle mediated targeting of VEGFR and cancer stem cells for cancer therapy
por: Ambasta, Rashmi K, et al.
Publicado: (2011)

Multiple therapeutic effect of endothelial progenitor cell regulated by drugs in diabetes and diabetes related disorder
por: Ambasta, Rashmi K., et al.
Publicado: (2017)

In silico designing of putative peptides for targeting pathological protein Htt in Huntington's disease
por: Kohli, Harleen, et al.
Publicado: (2021)

Artificial intelligence to deep learning: machine intelligence approach for drug discovery
por: Gupta, Rohan, et al.
Publicado: (2021)

CRISPR/Cas9 gene editing: New hope for Alzheimer's disease therapeutics
por: Bhardwaj, Shanu, et al.
Publicado: (2021)

Unboxing the molecular modalities of mutagens in cancer
por: Kumari, Smita, et al.
Publicado: (2021)

Computational Analysis Indicates That PARP1 Acts as a Histone Deacetylases Interactor Sharing Common Lysine Residues for Acetylation, Ubiquitination, and SUMOylation in Alzheimer’s and Parkinson’s Disease
por: Gupta, Rohan, et al.
Publicado: (2021)

Neuroprotective Role of Quercetin against Alpha-Synuclein-Associated Hallmarks in Parkinson’s Disease
por: Das, Sabya Sachi, et al.
Publicado: (2023)

α-Bisabolol, a Dietary Sesquiterpene, Attenuates Doxorubicin-Induced Acute Cardiotoxicity in Rats by Inhibiting Cellular Signaling Pathways, Nrf2/Keap-1/HO-1, Akt/mTOR/GSK-3β, NF-κB/p38/MAPK, and NLRP3 Inflammasomes Regulating Oxidative Stress and Inflammatory Cascades
por: Nagoor Meeran, Mohamed Fizur, et al.
Publicado: (2023)

Deciphering the SSR incidences across viral members of Coronaviridae family
por: Satyam, Rohit, et al.
Publicado: (2020)

Astragalus Polysaccharide Suppresses Doxorubicin-Induced Cardiotoxicity by Regulating the PI3k/Akt and p38MAPK Pathways
por: Cao, Yuan, et al.
Publicado: (2014)

Hesperetin Inhibits Vascular Formation by Suppressing of the PI3K/AKT, ERK, and p38 MAPK Signaling Pathways
por: Kim, Gi Dae
Publicado: (2014)

A “NOTCH” Deeper into the Epithelial-To-Mesenchymal Transition (EMT) Program in Breast Cancer
por: Kar, Rohan, et al.
Publicado: (2019)

HIV-1 Nef Induces CCL5 production in astrocytes through p38-MAPK and PI3K/Akt pathway and utilizes NF-kB, CEBP and AP-1 transcription factors
por: Liu, Xun, et al.
Publicado: (2014)

Mutational heterogeneity in spike glycoproteins of severe acute respiratory syndrome coronavirus 2
por: Mathur, Aanchal, et al.
Publicado: (2021)

Erianin suppresses hepatocellular carcinoma cells through down-regulation of PI3K/AKT, p38 and ERK MAPK signaling pathways
por: Yang, Liang, et al.
Publicado: (2020)

Fucoidan Induces Apoptosis and Inhibits Proliferation of Hepatocellular Carcinoma via the p38 MAPK/ERK and PI3K/Akt Signal Pathways
por: Duan, Yifei, et al.
Publicado: (2020)

Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin
por: Thomas, Shilu Deepa, et al.
Publicado: (2023)

The Role of PI3K/AKT and MAPK Signaling Pathways in Erythropoietin Signalization
por: Tóthová, Zuzana, et al.
Publicado: (2021)

Essential Oil from Zingiber ottensii Induces Human Cervical Cancer Cell Apoptosis and Inhibits MAPK and PI3K/AKT Signaling Cascades
por: Ruttanapattanakul, Jirapak, et al.
Publicado: (2021)

Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis by regulating p38 MAPKs and PI3K/AKT signaling pathways
por: Pan, Bo-Syong, et al.
Publicado: (2015)

The Apoptotic Effect of Ursolic Acid on SK-Hep-1 Cells is Regulated by the PI3K/Akt, p38 and JNK MAPK Signaling Pathways
por: Chuang, Wan-Ling, et al.
Publicado: (2016)

Cepharanthine Suppresses Herpes Simplex Virus Type 1 Replication Through the Downregulation of the PI3K/Akt and p38 MAPK Signaling Pathways
por: Liu, Yao, et al.
Publicado: (2021)

IL-1β Promotes Vasculogenic Mimicry of Breast Cancer Cells Through p38/MAPK and PI3K/Akt Signaling Pathways
por: Nisar, Muhammad Azhar, et al.
Publicado: (2021)

Sophoridine Suppresses Herpes Simplex Virus Type 1 Infection by Blocking the Activation of Cellular PI3K/Akt and p38 MAPK Pathways
por: Tang, Qiong, et al.
Publicado: (2022)

Deoxypodophyllotoxin Induces ROS-Mediated Apoptosis by Modulating the PI3K/AKT and p38 MAPK-Dependent Signaling in Oral Squamous Cell Carcinoma
por: Seo, Ji-Hye, et al.
Publicado: (2022)

β-Eudesmol Inhibits the Migration of Cholangiocarcinoma Cells by Suppressing Epithelial-Mesenchymal Transition via PI3K/AKT and p38MAPK Modulation
por: Acharya, Bishwanath, et al.
Publicado: (2022)

Corrigendum to: Deoxypodophyllotoxin Induces ROSMediated Apoptosis by Modulating the PI3K/AKT and p38 MAPK-Dependent Signaling in Oral Squamous Cell Carcinoma
por: Seo, Ji-Hye, et al.
Publicado: (2022)

Leaf Extract of Perilla frutescens (L.) Britt Promotes Adipocyte Browning via the p38 MAPK Pathway and PI3K-AKT Pathway
por: Chen, Fancheng, et al.
Publicado: (2023)

Antioxidants in Alzheimer’s Disease: Current Therapeutic Significance and Future Prospects
por: Pritam, Pingal, et al.
Publicado: (2022)

Computational Modeling of PI3K/AKT and MAPK Signaling Pathways in Melanoma Cancer
por: Pappalardo, Francesco, et al.
Publicado: (2016)

Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways
por: Yang, Tingfang, et al.
Publicado: (2016)

Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways
por: Hu, Zhiyan, et al.
Publicado: (2020)

RNA-binding proteins as a point of convergence of the PI3K and p38 MAPK pathways
por: Venigalla, Ram K. C., et al.
Publicado: (2012)

Evidence of Coronavirus (CoV) Pathogenesis and Emerging Pathogen SARS-CoV-2 in the Nervous System: A Review on Neurological Impairments and Manifestations
por: Jha, Niraj Kumar, et al.
Publicado: (2021)

Oxidative Stress in Cancer Cell Metabolism
por: Arfin, Saniya, et al.
Publicado: (2021)

The Emerging Role of Epigenetics in Metabolism and Endocrinology
por: Sibuh, Belay Zeleke, et al.
Publicado: (2023)

Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways
por: Jie, P, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_106duempuic3h5gr2qhg9jl0tp