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Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013
BACKGROUND: Diagnostic methods for pulmonary tuberculosis (TB) have recently advanced. The aim of this study was to evaluate the changes in TB diagnostic tests that prompted the initiation of anti-TB treatment over time in South Korea, an industrialized country with an intermediate TB burden. METHOD...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Tuberculosis and Respiratory Diseases
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499590/ https://www.ncbi.nlm.nih.gov/pubmed/26175776 http://dx.doi.org/10.4046/trd.2015.78.3.227 |
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author | Ahn, Bin Kim, Joohae Yoo, Chul-Gyu Kim, Young Whan Han, Sung Koo Yim, Jae-Joon |
author_facet | Ahn, Bin Kim, Joohae Yoo, Chul-Gyu Kim, Young Whan Han, Sung Koo Yim, Jae-Joon |
author_sort | Ahn, Bin |
collection | PubMed |
description | BACKGROUND: Diagnostic methods for pulmonary tuberculosis (TB) have recently advanced. The aim of this study was to evaluate the changes in TB diagnostic tests that prompted the initiation of anti-TB treatment over time in South Korea, an industrialized country with an intermediate TB burden. METHODS: Patients diagnosed with pulmonary TB in the first halves of 2005 and 2013 at a tertiary referral hospital were included. Diagnostic methods that prompted the initiation of anti-TB treatment were compared between the 2 groups of patients. RESULTS: A greater proportion of patients were diagnosed with pulmonary TB using bronchoscopy in 2013 than in 2005 (26.7% vs. 6.6%, respectively; p<0.001), while the proportion of patients clinically diagnosed with pulmonary TB was lower in 2013 than in 2005 (24.7% vs. 49.0%, respectively; p<0.001). Additionally, more patients started anti-TB treatment based on positive polymerase chain reaction (PCR) results for Mycobacterium tuberculosis DNA in 2013 than in 2005 (47.3% vs. 7.9%, respectively; p<0.001). CONCLUSION: The initiation of treatment for pulmonary TB in South Korea has become more frequently based on PCR and the use of bronchoscopic specimens. |
format | Online Article Text |
id | pubmed-4499590 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The Korean Academy of Tuberculosis and Respiratory Diseases |
record_format | MEDLINE/PubMed |
spelling | pubmed-44995902015-07-14 Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013 Ahn, Bin Kim, Joohae Yoo, Chul-Gyu Kim, Young Whan Han, Sung Koo Yim, Jae-Joon Tuberc Respir Dis (Seoul) Original Article BACKGROUND: Diagnostic methods for pulmonary tuberculosis (TB) have recently advanced. The aim of this study was to evaluate the changes in TB diagnostic tests that prompted the initiation of anti-TB treatment over time in South Korea, an industrialized country with an intermediate TB burden. METHODS: Patients diagnosed with pulmonary TB in the first halves of 2005 and 2013 at a tertiary referral hospital were included. Diagnostic methods that prompted the initiation of anti-TB treatment were compared between the 2 groups of patients. RESULTS: A greater proportion of patients were diagnosed with pulmonary TB using bronchoscopy in 2013 than in 2005 (26.7% vs. 6.6%, respectively; p<0.001), while the proportion of patients clinically diagnosed with pulmonary TB was lower in 2013 than in 2005 (24.7% vs. 49.0%, respectively; p<0.001). Additionally, more patients started anti-TB treatment based on positive polymerase chain reaction (PCR) results for Mycobacterium tuberculosis DNA in 2013 than in 2005 (47.3% vs. 7.9%, respectively; p<0.001). CONCLUSION: The initiation of treatment for pulmonary TB in South Korea has become more frequently based on PCR and the use of bronchoscopic specimens. The Korean Academy of Tuberculosis and Respiratory Diseases 2015-07 2015-06-30 /pmc/articles/PMC4499590/ /pubmed/26175776 http://dx.doi.org/10.4046/trd.2015.78.3.227 Text en Copyright©2015. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ It is identical to the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Original Article Ahn, Bin Kim, Joohae Yoo, Chul-Gyu Kim, Young Whan Han, Sung Koo Yim, Jae-Joon Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013 |
title | Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013 |
title_full | Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013 |
title_fullStr | Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013 |
title_full_unstemmed | Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013 |
title_short | Changes in Diagnostic Methods for Pulmonary Tuberculosis between 2005 and 2013 |
title_sort | changes in diagnostic methods for pulmonary tuberculosis between 2005 and 2013 |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499590/ https://www.ncbi.nlm.nih.gov/pubmed/26175776 http://dx.doi.org/10.4046/trd.2015.78.3.227 |
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