β-Elemene Inhibits Cell Proliferation by Regulating the Expression and Activity of Topoisomerases I and IIα in Human Hepatocarcinoma HepG-2 Cells

Objective. To investigate the effects of β-Elemene (β-ELE) on the proliferation, apoptosis, and topoisomerase I (TOPO I) and topoisomerase IIα (TOPO IIα) expression and activity of human hepatocarcinoma HepG-2 cells. Methods. After treatment with β-ELE, morphological alterations of HepG-2 cells were...

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Detalles Bibliográficos
Autores principales: Gong, Min, Liu, Ying, Zhang, Jian, Gao, Ya-jie, Zhai, Ping-ping, Su, Xi, Li, Xiang, Li, Yan, Hou, Li, Cui, Xiao-nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499621/
https://www.ncbi.nlm.nih.gov/pubmed/26221582
http://dx.doi.org/10.1155/2015/153987

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