Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells

Tyrosine kinase inhibitors (TKIs) are mostly used in non-small cell lung cancer (NSCLC) treatment. Unfortunately, treatment with Gefitinib for a period of time will result in drug resistance and cause treatment failure in clinic. Therefore, exploring novel compounds to overcome this resistance is ur...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Wei, Liu, Ying, Zhang, Ran, Zhang, Bo, Wang, Teng, Zhu, Xianbing, Mei, Lin, Chen, Hongbo, Zhang, Hongling, Ming, Pinghong, Huang, Laiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499885/
https://www.ncbi.nlm.nih.gov/pubmed/26166037
http://dx.doi.org/10.1038/srep08477

Ejemplares similares

Ejemplares similares