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Acquired transmissibility of sheep-passaged L-type bovine spongiform encephalopathy prion to wild-type mice

L-type bovine spongiform encephalopathy (L-BSE) is an atypical form of BSE that is transmissible to cattle and several lines of prion protein (PrP) transgenic mice, but not to wild-type mice. In this study, we examined the transmissibility of sheep-passaged L-BSE prions to wild-type mice. Disease-as...

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Detalles Bibliográficos
Autores principales: Okada, Hiroyuki, Masujin, Kentaro, Miyazawa, Kohtaro, Yokoyama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499898/
https://www.ncbi.nlm.nih.gov/pubmed/26169916
http://dx.doi.org/10.1186/s13567-015-0211-2

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