Intermolecular epistasis shaped the function and evolution of an ancient transcription factor and its DNA binding sites

Complexes of specifically interacting molecules, such as transcription factor proteins (TFs) and the DNA response elements (REs) they recognize, control most biological processes, but little is known concerning the functional and evolutionary effects of epistatic interactions across molecular interf...

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Detalles Bibliográficos
Autores principales: Anderson, Dave W, McKeown, Alesia N, Thornton, Joseph W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Genomics and Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500092/
https://www.ncbi.nlm.nih.gov/pubmed/26076233
http://dx.doi.org/10.7554/eLife.07864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500092/
https://www.ncbi.nlm.nih.gov/pubmed/26076233
http://dx.doi.org/10.7554/eLife.07864

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