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Intermolecular epistasis shaped the function and evolution of an ancient transcription factor and its DNA binding sites
Complexes of specifically interacting molecules, such as transcription factor proteins (TFs) and the DNA response elements (REs) they recognize, control most biological processes, but little is known concerning the functional and evolutionary effects of epistatic interactions across molecular interf...
Autores principales: | Anderson, Dave W, McKeown, Alesia N, Thornton, Joseph W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500092/ https://www.ncbi.nlm.nih.gov/pubmed/26076233 http://dx.doi.org/10.7554/eLife.07864 |
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