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Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe

Synthetic genetic array (SGA) has been successfully used to identify genetic interactions in S. cerevisiae and S. pombe. In S. pombe, SGA methods use either cycloheximide (C) or heat shock (HS) to select double mutants before measuring colony size as a surrogate for fitness. Quantitative Fitness Ana...

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Detalles Bibliográficos
Autores principales:	Narayanan, Siddharth, Dubarry, Marion, Lawless, Conor, Banks, A. Peter, Wilkinson, Darren J., Whitehall, Simon K., Lydall, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500466/ https://www.ncbi.nlm.nih.gov/pubmed/26168240 http://dx.doi.org/10.1371/journal.pone.0132240

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