Lymphangioleiomyomatosis Biomarkers Linked to Lung Metastatic Potential and Cell Stemness

Lymphangioleiomyomatosis (LAM) is a rare lung-metastasizing neoplasm caused by the proliferation of smooth muscle-like cells that commonly carry loss-of-function mutations in either the tuberous sclerosis complex 1 or 2 (TSC1 or TSC2) genes. While allosteric inhibition of the mechanistic target of r...

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Detalles Bibliográficos
Autores principales: Ruiz de Garibay, Gorka, Herranz, Carmen, Llorente, Alicia, Boni, Jacopo, Serra-Musach, Jordi, Mateo, Francesca, Aguilar, Helena, Gómez-Baldó, Laia, Petit, Anna, Vidal, August, Climent, Fina, Hernández-Losa, Javier, Cordero, Álex, González-Suárez, Eva, Sánchez-Mut, José Vicente, Esteller, Manel, Llatjós, Roger, Varela, Mar, López, José Ignacio, García, Nadia, Extremera, Ana I., Gumà, Anna, Ortega, Raúl, Plà, María Jesús, Fernández, Adela, Pernas, Sònia, Falo, Catalina, Morilla, Idoia, Campos, Miriam, Gil, Miguel, Román, Antonio, Molina-Molina, María, Ussetti, Piedad, Laporta, Rosalía, Valenzuela, Claudia, Ancochea, Julio, Xaubet, Antoni, Casanova, Álvaro, Pujana, Miguel Angel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500593/
https://www.ncbi.nlm.nih.gov/pubmed/26167915
http://dx.doi.org/10.1371/journal.pone.0132546

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