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Utility of a high VWF:FVIII ratio in preventing FVIII accumulation: a study in VWF-deficient mice
Treatment of von Willebrand disease typically requires multiple infusions of von Willebrand factor (VWF)/factor VIII (FVIII) concentrate. Accumulation of FVIII is a clinical concern due to potential risk for thromboembolism. This study sought to determine whether VWF/FVIII concentrate of high VWF:FV...
Autores principales: | Raquet, Elmar, Stockschlaeder, Marcus, Mueller-Cohrs, Jochen, Zollner, Sabine, Pragst, Ingo, Dickneite, Gerhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams And Wilkins
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500654/ https://www.ncbi.nlm.nih.gov/pubmed/25767894 http://dx.doi.org/10.1097/MBC.0000000000000269 |
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