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A Novel Type of Non-coding RNA, nc886, Implicated in Tumor Sensing and Suppression

nc886 (=vtRNA2-1, pre-miR-886, or CBL3) is a newly identified non-coding RNA (ncRNA) that represses the activity of protein kinase R (PKR). nc886 is transcribed by RNA polymerase III (Pol III) and is intriguingly the first case of a Pol III gene whose expression is silenced by CpG DNA hypermethylati...

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Detalles Bibliográficos
Autor principal: Lee, Yong Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500795/
https://www.ncbi.nlm.nih.gov/pubmed/26175659
http://dx.doi.org/10.5808/GI.2015.13.2.26

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