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Modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation
This study examines with transcranial magnetic stimulation (TMS) and with functional magnetic resonance imaging (fMRI) whether 20 min of repetitive peripheral magnetic stimulation (rPMS) has a facilitating effect on associated motor controlling regions. Trains of rPMS with a stimulus intensity of 15...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500907/ https://www.ncbi.nlm.nih.gov/pubmed/26236220 http://dx.doi.org/10.3389/fnhum.2015.00407 |
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author | Gallasch, Eugen Christova, Monica Kunz, Alexander Rafolt, Dietmar Golaszewski, Stefan |
author_facet | Gallasch, Eugen Christova, Monica Kunz, Alexander Rafolt, Dietmar Golaszewski, Stefan |
author_sort | Gallasch, Eugen |
collection | PubMed |
description | This study examines with transcranial magnetic stimulation (TMS) and with functional magnetic resonance imaging (fMRI) whether 20 min of repetitive peripheral magnetic stimulation (rPMS) has a facilitating effect on associated motor controlling regions. Trains of rPMS with a stimulus intensity of 150% of the motor threshold (MT) were applied over right hand flexor muscles of healthy volunteers. First, with TMS, 10 vs. 25 Hz rPMS was examined and compared to a control group. Single and paired pulse motor evoked potentials (MEPs) from flexor carpi radialis (FCR) and extensor carpi radialis (ECR) muscles were recorded at baseline (T0), post rPMS (T1), 30 min post (T2), 1 h post (T3) and 2 h post rPMS (T4). Then, with fMRI, 25 Hz rPMS was compared to sham stimulation by utilizing a finger tapping activation paradigm. Changes in bloodoxygen level dependent (BOLD) contrast were examined at baseline (PRE), post rPMS (POST1) and 1 h post rPMS (POST2). With TMS facilitation was observed in the target muscle (FCR) following 25 Hz rPMS: MEP recruitment curves (RCs) were increased at T1, T2 and T3, and intracortical facilitation (ICF) was increased at T1 and T2. No effects were observed following 10 Hz rPMS. With fMRI the BOLD contrast at the left sensorimotor area was increased at POST1. Compared to inductions protocols based on transcutaneous electrical stimulation and mechanical stimulation, the rPMS induced effects appeared shorter lasting. |
format | Online Article Text |
id | pubmed-4500907 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-45009072015-07-31 Modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation Gallasch, Eugen Christova, Monica Kunz, Alexander Rafolt, Dietmar Golaszewski, Stefan Front Hum Neurosci Neuroscience This study examines with transcranial magnetic stimulation (TMS) and with functional magnetic resonance imaging (fMRI) whether 20 min of repetitive peripheral magnetic stimulation (rPMS) has a facilitating effect on associated motor controlling regions. Trains of rPMS with a stimulus intensity of 150% of the motor threshold (MT) were applied over right hand flexor muscles of healthy volunteers. First, with TMS, 10 vs. 25 Hz rPMS was examined and compared to a control group. Single and paired pulse motor evoked potentials (MEPs) from flexor carpi radialis (FCR) and extensor carpi radialis (ECR) muscles were recorded at baseline (T0), post rPMS (T1), 30 min post (T2), 1 h post (T3) and 2 h post rPMS (T4). Then, with fMRI, 25 Hz rPMS was compared to sham stimulation by utilizing a finger tapping activation paradigm. Changes in bloodoxygen level dependent (BOLD) contrast were examined at baseline (PRE), post rPMS (POST1) and 1 h post rPMS (POST2). With TMS facilitation was observed in the target muscle (FCR) following 25 Hz rPMS: MEP recruitment curves (RCs) were increased at T1, T2 and T3, and intracortical facilitation (ICF) was increased at T1 and T2. No effects were observed following 10 Hz rPMS. With fMRI the BOLD contrast at the left sensorimotor area was increased at POST1. Compared to inductions protocols based on transcutaneous electrical stimulation and mechanical stimulation, the rPMS induced effects appeared shorter lasting. Frontiers Media S.A. 2015-07-14 /pmc/articles/PMC4500907/ /pubmed/26236220 http://dx.doi.org/10.3389/fnhum.2015.00407 Text en Copyright © 2015 Gallasch, Christova, Kunz, Rafolt and Golaszewski. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Gallasch, Eugen Christova, Monica Kunz, Alexander Rafolt, Dietmar Golaszewski, Stefan Modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation |
title | Modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation |
title_full | Modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation |
title_fullStr | Modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation |
title_full_unstemmed | Modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation |
title_short | Modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation |
title_sort | modulation of sensorimotor cortex by repetitive peripheral magnetic stimulation |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500907/ https://www.ncbi.nlm.nih.gov/pubmed/26236220 http://dx.doi.org/10.3389/fnhum.2015.00407 |
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