Cargando…
Automated astatination of biomolecules – a stepping stone towards multicenter clinical trials
To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical and physi...
Autores principales: | Aneheim, Emma, Albertsson, Per, Bäck, Tom, Jensen, Holger, Palm, Stig, Lindegren, Sture |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500947/ https://www.ncbi.nlm.nih.gov/pubmed/26169786 http://dx.doi.org/10.1038/srep12025 |
Ejemplares similares
-
Realizing Clinical Trials with Astatine-211: The Chemistry Infrastructure
por: Lindegren, Sture, et al.
Publicado: (2020) -
Towards elucidating the radiochemistry of astatine – Behavior in chloroform
por: Aneheim, Emma, et al.
Publicado: (2019) -
Astatine-211 based radionuclide therapy: Current clinical trial landscape
por: Albertsson, Per, et al.
Publicado: (2023) -
Pretargeted Alpha Therapy of Disseminated Cancer Combining Click Chemistry and Astatine-211
por: Timperanza, Chiara, et al.
Publicado: (2023) -
Evaluation of therapeutic efficacy of (211)At-labeled farletuzumab in an intraperitoneal mouse model of disseminated ovarian cancer
por: Palm, Stig, et al.
Publicado: (2020)