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Ortho-methylated 3-hydroxypyridines hinder hen egg-white lysozyme fibrillogenesis
Protein aggregation with the concomitant formation of amyloid fibrils is related to several neurodegenerative diseases, but also to non-neuropathic amyloidogenic diseases and non-neurophatic systemic amyloidosis. Lysozyme is the protein involved in the latter, and it is widely used as a model system...
Autores principales: | Mariño, Laura, Pauwels, Kris, Casasnovas, Rodrigo, Sanchis, Pilar, Vilanova, Bartolomé, Muñoz, Francisco, Donoso, Josefa, Adrover, Miquel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500996/ https://www.ncbi.nlm.nih.gov/pubmed/26169912 http://dx.doi.org/10.1038/srep12052 |
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