NKCC1 downregulation induces hyperpolarizing shift of GABA responsiveness at near term fetal stages in rat cultured dorsal root ganglion neurons

BACKGROUND: GABA(A) receptor-mediated neurotransmission is greatly influenced by cation-chloride cotransporter activity during developmental stages. In embryonic neurons Na–K–2Cl (NKCC1) cotransporters mediate active chloride uptake, thus increasing the intracellular chloride concentration associate...

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Detalles Bibliográficos
Autores principales: Chabwine, Joelle N, Talavera, Karel, Van Den Bosch, Ludo, Callewaert, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501047/
https://www.ncbi.nlm.nih.gov/pubmed/26169500
http://dx.doi.org/10.1186/s12868-015-0180-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501047/
https://www.ncbi.nlm.nih.gov/pubmed/26169500
http://dx.doi.org/10.1186/s12868-015-0180-4

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