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An integrative pan-cancer-wide analysis of epigenetic enzymes reveals universal patterns of epigenomic deregulation in cancer
BACKGROUND: One of the most important recent findings in cancer genomics is the identification of novel driver mutations which often target genes that regulate genome-wide chromatin and DNA methylation marks. Little is known, however, as to whether these genes exhibit patterns of epigenomic deregula...
Autores principales: | Yang, Zhen, Jones, Allison, Widschwendter, Martin, Teschendorff, Andrew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501092/ https://www.ncbi.nlm.nih.gov/pubmed/26169266 http://dx.doi.org/10.1186/s13059-015-0699-9 |
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