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Shiga toxin type-2 (Stx2) induces glutamate release via phosphoinositide 3-kinase (PI3K) pathway in murine neurons

Shiga toxin-producing Escherichia coli (STEC) can cause central nervous system (CNS) damage resulting in paralysis, seizures, and coma. The key STEC virulence factors associated with systemic illness resulting in CNS impairment are Shiga toxins (Stx). While neurons express the Stx receptor globotria...

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Detalles Bibliográficos
Autores principales:	Obata, Fumiko, Hippler, Lauren M., Saha, Progyaparamita, Jandhyala, Dakshina M., Latinovic, Olga S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501177/ https://www.ncbi.nlm.nih.gov/pubmed/26236186 http://dx.doi.org/10.3389/fnmol.2015.00030

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