Broad protection with an inactivated vaccine against primary-isolated lethal enterovirus 71 infection in newborn mice

BACKGROUND: Circulating enterovirus 71 (EV-A71)-associated hand, foot, and mouth disease is on the rise in the Asian-Pacific region. Although animal models have been developed using mouse-adapted EV-A71 strains, mouse models using primary EV-A71 isolates are scarce. Lethal animal models with circula...

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Detalles Bibliográficos
Autores principales: Chang, Junliang, Li, Jingliang, Liu, Xin, Liu, Guanchen, Yang, Jiaxin, Wei, Wei, Zhang, Wenyan, Yu, Xiao-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501189/
https://www.ncbi.nlm.nih.gov/pubmed/26169371
http://dx.doi.org/10.1186/s12866-015-0474-9

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