Cargando…

Establishing the UK DNA Bank for motor neuron disease (MND)

In 2003 the Motor Neurone Disease (MND) Association, together with The Wellcome Trust, funded the creation of a national DNA Bank specific for MND. It was anticipated that the DNA Bank would constitute an important resource to researchers worldwide and significantly increase activity in MND genetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Smith, Lucy, Cupid, B. C., Dickie, B. G. M., Al-Chalabi, A., Morrison, K. E., Shaw, C. E., Shaw, P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501191/
https://www.ncbi.nlm.nih.gov/pubmed/26170009
http://dx.doi.org/10.1186/s12863-015-0236-6
Descripción
Sumario:In 2003 the Motor Neurone Disease (MND) Association, together with The Wellcome Trust, funded the creation of a national DNA Bank specific for MND. It was anticipated that the DNA Bank would constitute an important resource to researchers worldwide and significantly increase activity in MND genetic research. The DNA Bank houses over 3000 high quality DNA samples, all of which were donated by people living with MND, family members and non-related controls, accompanied by clinical phenotype data about the patients. Today the primary focus of the UK MND DNA Bank still remains to identify causative and disease modifying factors for this devastating disease. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12863-015-0236-6) contains supplementary material, which is available to authorized users.