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A semi-supervised approach uncovers thousands of intragenic enhancers differentially activated in human cells
BACKGROUND: Transcriptional enhancers are generally known to regulate gene transcription from afar. Their activation involves a series of changes in chromatin marks and recruitment of protein factors. These enhancers may also occur inside genes, but how many may be active in human cells and their ef...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501197/ https://www.ncbi.nlm.nih.gov/pubmed/26169177 http://dx.doi.org/10.1186/s12864-015-1704-0 |