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A semi-supervised approach uncovers thousands of intragenic enhancers differentially activated in human cells

BACKGROUND: Transcriptional enhancers are generally known to regulate gene transcription from afar. Their activation involves a series of changes in chromatin marks and recruitment of protein factors. These enhancers may also occur inside genes, but how many may be active in human cells and their ef...

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Detalles Bibliográficos
Autores principales:	González-Vallinas, Juan, Pagès, Amadís, Singh, Babita, Eyras, Eduardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501197/ https://www.ncbi.nlm.nih.gov/pubmed/26169177 http://dx.doi.org/10.1186/s12864-015-1704-0

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