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An optimized TALEN application for mutagenesis and screening in Drosophila melanogaster

Transcription activator-like effector nucleases (TALENs) emerged as powerful tools for locus-specific genome engineering. Due to the ease of TALEN assembly, the key to streamlining TALEN-induced mutagenesis lies in identifying efficient TALEN pairs and optimizing TALEN mRNA injection concentrations...

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Detalles Bibliográficos
Autores principales:	Lee, Han B, Sebo, Zachary L, Peng, Ying, Guo, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Methods and Technologies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501208/ https://www.ncbi.nlm.nih.gov/pubmed/26196022 http://dx.doi.org/10.1080/21592799.2015.1023423

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