Cargando…
Manipulating megakaryocytes to manufacture platelets ex vivo
Historically, platelet transfusion has proven a reliable way to treat patients suffering from thrombocytopenia or similar ailments. An undersupply of donors, however, has demanded alternative platelet sources. Scientists have therefore sought to recapitulate the biological events that convert hemato...
Autores principales: | Karagiannis, P, Eto, K |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501322/ https://www.ncbi.nlm.nih.gov/pubmed/26149050 http://dx.doi.org/10.1111/jth.12946 |
Ejemplares similares
-
Increased expression of HIF2α during iron deficiency–associated megakaryocytic differentiation
por: Jimenez, K., et al.
Publicado: (2015) -
The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production
por: Heazlewood, Shen Y., et al.
Publicado: (2022) -
Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion
por: Leatherdale, Alexander, et al.
Publicado: (2020) -
Megakaryocyte/platelet-derived TGF-β1 inhibits megakaryopoiesis in bone marrow by regulating thrombopoietin production in liver
por: Gostynska, Sandra, et al.
Publicado: (2022) -
Transcriptomic Analysis of the Ion Channelome of Human Platelets and Megakaryocytic Cell Lines
por: Wright, Joy R., et al.
Publicado: (2016)