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ATF4 licenses C/EBPβ activity in human mesenchymal stem cells primed for adipogenesis

A well-established cascade of transcription factor (TF) activity orchestrates adipogenesis in response to chemical cues, yet how cell-intrinsic determinants of differentiation such as cell shape and/or seeding density inform this transcriptional program remain enigmatic. Here, we uncover a novel mec...

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Detalles Bibliográficos
Autores principales: Cohen, Daniel M, Won, Kyoung-Jae, Nguyen, Nha, Lazar, Mitchell A, Chen, Christopher S, Steger, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501333/
https://www.ncbi.nlm.nih.gov/pubmed/26111340
http://dx.doi.org/10.7554/eLife.06821