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Protein degradation corrects for imbalanced subunit stoichiometry in OST complex assembly

Protein degradation is essential for cellular homeostasis. We developed a sensitive approach to examining protein degradation rates in Saccharomyces cerevisiae by coupling a SILAC approach to selected reaction monitoring (SRM) mass spectrometry. Combined with genetic tools, this analysis made it pos...

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Detalles Bibliográficos
Autores principales:	Mueller, Susanne, Wahlander, Asa, Selevsek, Nathalie, Otto, Claudia, Ngwa, Elsy Mankah, Poljak, Kristina, Frey, Alexander D., Aebi, Markus, Gauss, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501358/ https://www.ncbi.nlm.nih.gov/pubmed/25995378 http://dx.doi.org/10.1091/mbc.E15-03-0168

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