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The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane

Many Rab GTPase effectors are membrane-tethering factors, that is, they physically link two apposed membranes before intracellular membrane fusion. In this study, we investigate the distinct binding factors needed on apposed membranes for Rab effector–dependent tethering. We show that the homotypic...

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Detalles Bibliográficos
Autores principales: Ho, Ruoya, Stroupe, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501362/
https://www.ncbi.nlm.nih.gov/pubmed/25995379
http://dx.doi.org/10.1091/mbc.E14-04-0922