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The HOPS/class C Vps complex tethers membranes by binding to one Rab GTPase in each apposed membrane
Many Rab GTPase effectors are membrane-tethering factors, that is, they physically link two apposed membranes before intracellular membrane fusion. In this study, we investigate the distinct binding factors needed on apposed membranes for Rab effector–dependent tethering. We show that the homotypic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501362/ https://www.ncbi.nlm.nih.gov/pubmed/25995379 http://dx.doi.org/10.1091/mbc.E14-04-0922 |