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Mycalolide B dissociates dynactin and abolishes retrograde axonal transport of dense-core vesicles

Axonal transport is critical for maintaining synaptic transmission. Of interest, anterograde and retrograde axonal transport appear to be interdependent, as perturbing one directional motor often impairs movement in the opposite direction. Here live imaging of Drosophila and hippocampal neuron dense...

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Detalles Bibliográficos
Autores principales:	Cavolo, Samantha L., Zhou, Chaoming, Ketcham, Stephanie A., Suzuki, Matthew M., Ukalovic, Kresimir, Silverman, Michael A., Schroer, Trina A., Levitan, Edwin S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501363/ https://www.ncbi.nlm.nih.gov/pubmed/26023088 http://dx.doi.org/10.1091/mbc.E14-11-1564

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