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An ELMO2-RhoG-ILK network modulates microtubule dynamics

ELMO2 belongs to a family of scaffold proteins involved in phagocytosis and cell motility. ELMO2 can simultaneously bind integrin-linked kinase (ILK) and RhoG, forming tripartite ERI complexes. These complexes are involved in promoting β1 integrin–dependent directional migration in undifferentiated...

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Detalles Bibliográficos
Autores principales: Jackson, Bradley C., Ivanova, Iordanka A., Dagnino, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501367/
https://www.ncbi.nlm.nih.gov/pubmed/25995380
http://dx.doi.org/10.1091/mbc.E14-10-1444