Using a single tablet daily to treat latent tuberculosis infection in Brazil: bioequivalence of two different isoniazid formulations (300 mg and 100 mg) demonstrated by a sensitive and rapid high-performance liquid chromatography-tandem mass spectrometry method in a randomised, crossover study

The recommended treatment for latent tuberculosis (TB) infection in adults is a daily dose of isoniazid (INH) 300 mg for six months. In Brazil, INH was formulated as 100 mg tablets. The treatment duration and the high pill burden compromised patient adherence to the treatment. The Brazilian National...

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Detalles Bibliográficos
Autores principales: Daher, André, Pitta, Luciana, Santos, Tereza, Barreira, Draurio, Pinto, Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501419/
https://www.ncbi.nlm.nih.gov/pubmed/26038960
http://dx.doi.org/10.1590/0074-02760140458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501419/
https://www.ncbi.nlm.nih.gov/pubmed/26038960
http://dx.doi.org/10.1590/0074-02760140458

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