SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair

XPC recognizes UV-induced DNA lesions and initiates their removal by nucleotide excision repair (NER). Damage recognition in NER is tightly controlled by ubiquitin and SUMO modifications. Recent studies have shown that the SUMO-targeted ubiquitin ligase RNF111 promotes K63-linked ubiquitylation of S...

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Detalles Bibliográficos
Autores principales: van Cuijk, Loes, van Belle, Gijsbert J., Turkyilmaz, Yasemin, Poulsen, Sara L., Janssens, Roel C., Theil, Arjan F., Sabatella, Mariangela, Lans, Hannes, Mailand, Niels, Houtsmuller, Adriaan B., Vermeulen, Wim, Marteijn, Jurgen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501428/
https://www.ncbi.nlm.nih.gov/pubmed/26151477
http://dx.doi.org/10.1038/ncomms8499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501428/
https://www.ncbi.nlm.nih.gov/pubmed/26151477
http://dx.doi.org/10.1038/ncomms8499

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