An in vitro iron superoxide dismutase inhibitor decreases the parasitemia levels of Trypanosoma cruzi in BALB/c mouse model during acute phase

In order to identify new compounds to treat Chagas disease during the acute phase with higher activity and lower toxicity than the reference drug benznidazole (Bz), two hydroxyphthalazine derivative compounds were prepared and their trypanocidal effects against Trypanosoma cruzi were evaluated by li...

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Detalles Bibliográficos
Autores principales: Olmo, Francisco, Urbanová, Kristína, Rosales, Maria Jose, Martín-Escolano, Ruben, Sánchez-Moreno, Manuel, Marín, Clotilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501536/
https://www.ncbi.nlm.nih.gov/pubmed/26236582
http://dx.doi.org/10.1016/j.ijpddr.2015.05.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501536/
https://www.ncbi.nlm.nih.gov/pubmed/26236582
http://dx.doi.org/10.1016/j.ijpddr.2015.05.002

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