Vitamin K2 and cotylenin A synergistically induce monocytic differentiation and growth arrest along with the suppression of c-MYC expression and induction of cyclin G2 expression in human leukemia HL-60 cells

Although all-trans retinoic acid (ATRA) is a standard and effective drug used for differentiation therapy in acute promyelocytic leukemia, ATRA-resistant leukemia cells ultimately emerge during this treatment. Therefore, the development of new drugs or effective combination therapy is urgently neede...

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Detalles Bibliográficos
Autores principales: MANIWA, YASUHISA, KASUKABE, TAKASHI, KUMAKURA, SHUNICHI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501641/
https://www.ncbi.nlm.nih.gov/pubmed/26046133
http://dx.doi.org/10.3892/ijo.2015.3028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501641/
https://www.ncbi.nlm.nih.gov/pubmed/26046133
http://dx.doi.org/10.3892/ijo.2015.3028

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