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MicroRNA-125b-2 overexpression represses ectodermal differentiation of mouse embryonic stem cells
microRNAs (miRNAs or miRS) have been demonstrated to be essential for neural development. miR-125b-2, presented on human chromosome 21, is overexpressed in neurons of individuals with Down syndrome (DS) with cognitive impairments. It has been reported that miR-125b-2 promotes specific types of neuro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501654/ https://www.ncbi.nlm.nih.gov/pubmed/26059631 http://dx.doi.org/10.3892/ijmm.2015.2238 |