Cargando…

Acetaminophen induces JNK/p38 signaling and activates the caspase-9-3-dependent cell death pathway in human mesenchymal stem cells

Acetaminophen (APAP) is a widely used analgesic and antipyretic drug. Generally, the therapeutic dose of APAP is clinically safe, however, high doses of APAP can cause acute liver and kidney injury. Therefore, the majority of previous studies have focussed on elucidating the mechanisms of APAP-induc...

Descripción completa

Detalles Bibliográficos
Autores principales: YIANG, GIOU-TENG, YU, YUNG-LUNG, LIN, KO-TING, CHEN, JEN-NI, CHANG, WEI-JUNG, WEI, CHYOU-WEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501662/
https://www.ncbi.nlm.nih.gov/pubmed/26096646
http://dx.doi.org/10.3892/ijmm.2015.2254